Lace M. Riggs, M.A.
GRADUATE STUDENT PROGRAM IN NEUROSCIENCE
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Education
M.A. in Experimental Psychology, California State University, San Bernardino, CA B.A. in Biological Psychology, California State University, San Bernardino, CA Current Projects Examining the neurophysiological mechanisms of rapid antidepressant efficacy. Other Research Interests Neurodevelopment, addiction, epigenetics, research ethics, health disparities, diversity. Contact Information Email: lacemriggs[at]umaryland.edu Phone: (410) 706-6799 |
Description
I earned a B.A. in Biological Psychology and an M.A. in Experimental Psychology from California State University. There, I studied risk factors associated with enhanced susceptibility to adolescent depression, as well as the enduring neurobehavioral adaptations that result from antidepressant treatment during early development. My interests in synaptic plasticity and translational neuroscience approaches led me to the Gould Lab at the University of Maryland School of Medicine, where I am earning a Ph.D. in Neuroscience in the Graduate Program in Life Sciences. I am currently using behavioral, electrophysiological, and photometric approaches to investigate the mechanisms underlying the rapid antidepressant actions of the ketamine metabolite, (2R,6R)-hydroxynorketamine.
I earned a B.A. in Biological Psychology and an M.A. in Experimental Psychology from California State University. There, I studied risk factors associated with enhanced susceptibility to adolescent depression, as well as the enduring neurobehavioral adaptations that result from antidepressant treatment during early development. My interests in synaptic plasticity and translational neuroscience approaches led me to the Gould Lab at the University of Maryland School of Medicine, where I am earning a Ph.D. in Neuroscience in the Graduate Program in Life Sciences. I am currently using behavioral, electrophysiological, and photometric approaches to investigate the mechanisms underlying the rapid antidepressant actions of the ketamine metabolite, (2R,6R)-hydroxynorketamine.
funding
Current
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship
NIH National Institute of Mental Health (NIMH), F31-MH123066
“Synaptic mechanisms underlying the rapid antidepressant properties of the (2R,6R)-hydroxynorketamine metabolite.”
Completed
Training Program in Integrative Membrane Biology, UMSOM
NIH National Institute of General Medical Sciences (NIGMS), T32-GM008181
Student of Merit Award, Training Program in Neuroscience, UMSOM
NIH National Institute of Neurological Disorders and Stroke (NINDS), T32-NS063391
Meyerhoff Graduate Fellowship Program, Initiative for Maximizing Student Development, UMD
NIH National Institute of General Medical Sciences (NIGMS), R25-GM055036
Diversity Promoting Institutions Drug Abuse Research Program, CSU
NIH National Institute on Drug Abuse, R24-DA033877
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship
NIH National Institute of Mental Health (NIMH), F31-MH123066
“Synaptic mechanisms underlying the rapid antidepressant properties of the (2R,6R)-hydroxynorketamine metabolite.”
Completed
Training Program in Integrative Membrane Biology, UMSOM
NIH National Institute of General Medical Sciences (NIGMS), T32-GM008181
Student of Merit Award, Training Program in Neuroscience, UMSOM
NIH National Institute of Neurological Disorders and Stroke (NINDS), T32-NS063391
Meyerhoff Graduate Fellowship Program, Initiative for Maximizing Student Development, UMD
NIH National Institute of General Medical Sciences (NIGMS), R25-GM055036
Diversity Promoting Institutions Drug Abuse Research Program, CSU
NIH National Institute on Drug Abuse, R24-DA033877
selected publications
Riggs LM, Aracava Y, Zanos P, Fischell J, Albuquerque EX, Pereira EFR, Thompson SM, Gould TD (2019). (2R,6R)-hydroxynorketamine rapidly potentiates hippocampal glutamatergic transmission through a synapse-specific presynaptic mechanism. Neuropsychopharmacology, PMID: 31216563.
Zanos P, Moaddel R, Morris PJ, Riggs LM, Highland JN, Georgiou P, Pereira EFR, Albuquerque EX, Thomas CJ, Zarate CA Jr, Gould TD (2018). Ketamine and ketamine metabolite pharmacology: Insights into therapeutic mechanisms. Pharmacological Reviews, 70(3):621-660. PMID: 29945898.
For full list, please visit:
Zanos P, Moaddel R, Morris PJ, Riggs LM, Highland JN, Georgiou P, Pereira EFR, Albuquerque EX, Thomas CJ, Zarate CA Jr, Gould TD (2018). Ketamine and ketamine metabolite pharmacology: Insights into therapeutic mechanisms. Pharmacological Reviews, 70(3):621-660. PMID: 29945898.
For full list, please visit:
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